Hey,
I'm sorry about the problem you're having. It might help to get a better idea of what's going on, so I wanted to ask you a couple of quick questions. When you try to print from Edge, do you see the "DYMO Label Web Service" icon in the system tray near your clock? And when you try to open your Lightspeed POS Backoffice in another browser like Chrome or Firefox, does printing suddenly work there? These small tests can help us figure out if the problem is with the service or with Edge itself.
Hope to hear from you,
Thank you,